Wednesday, 31 December 2014

Good and bad effects of boredom

I’ve met lots of people with a talent to bore in my time, but Sandi Mann is one of the few to have honed it as a craft. Eager volunteers visiting her lab may be asked to carry out less-than-thrilling chores like copying out lengthy lists of telephone numbers. They mostly tolerate the task politely, she says, but their shuffling bottoms and regular yawns prove they are hardly relishing the experience.
Their agony is science’s gain, though, since Mann wants to understand the profound effect that boredom may have on our lives. So far, she is one of the few psychologists to have forayed into such mind-numbing territories. “It’s the Cinderella of psychology,” she says. After all, admitting that you study boredom might itself sound a bit, well, boring – but that is far from the truth. Boredom, it turns out, can be a dangerous and disruptive state of mind that damages your health – and even cuts years off your lifespan. If that sounds negative, Mann’s research would also suggest that without boredom we couldn’t achieve our creative feats.
Bored to death
Boredom is such a large part of day-to-day existence that it is somewhat surprising the word only entered the language with Charles Dickens’ Bleak House in 1852. Dickens study of Lady Deadlock’s suffering – she is “bored to death” by her marriage – would end up pre-empting many of the latest findings. But perhaps because of its prevalence in our lives, scientists had been slow to explore the sensation. “When you are swimming in something, maybe you don’t think of it as being noteworthy,” says John Eastwood at York University in Canada, who was one of the first scholars to take an interest.
One of the most common misconceptions is that “only boring people get bored”. Yet as Eastwood set about exploring the reasons for boredom, he found that there are two distinct types of personality that tend to suffer from ennui, and neither are particularly dull themselves.
Boredom often goes with a naturally impulsive mindset among people who are constantly looking for new experiences. For these people, the steady path of life just isn’t enough of a rollercoaster to hold their attention. “The world is chronically under-stimulating,” says Eastwood.
The second kind of bored people have almost exactly the opposite problem; the world is a fearful place, and so they shut themselves away and try not to step outside their comfort zone. “Out of their high-sensitivity to pain, they withdraw.” While this retreat might offer some comfort, they are not always satisfied with the safety it offers – and chronic boredom results.
(Thinkstock)
Tedium can push you to self-destruction (Thinkstock)
Almost from the very beginning, it became clear that either of these states could push people to harm themselves; a proneness to boredom was linked to a tendency to smoke, drink too much, and take drugs. Indeed, in one study boredom was thesingle biggest predictor of alcohol, cigarette and cannabis use among a group of South African teenagers.
That’s not to mention more mundane but equally unhealthy behaviours, such as comfort-eating your way through tedium. “Boredom at work is propping up the confectionary industry,” says Mann, who is based at the University of Central Lancashire, UK. The overall effect of boredom on your life expectancy could be drastic, too. When researchers in the famous Whitehall study followed the lives of middle-aged civil servants in the UK, they found that the people who are most likely to get bored were 30% more likely to have died over the next three years.
That is something of a puzzle for evolutionary psychologists. Emotions should evolve for our benefit – not to push us to self-destruction. “The very fact that boredom is a daily experience suggests it should be doing something useful,” says Heather Lench at Texas A&M University. Feelings like fear help us avoid danger, after all, while sadness might help prevent future mistakes. So, if true, what does boredom achieve?
(Thinkstock)
Without boredom, humans would not have the taste for adventure and exploration that makes us unique (Thinkstock)
Reviewing the evidence so far, Lench suspects that it lies behind one of our most important traits – curiosity. Boredom, she says, stops us ploughing the same old furrow, and pushes us to try to seek new goals or explore new territories or ideas. That search for an escape could sometimes push us to take risks that eventually hurt us. One team simply left subjects by themselves in a room for 15 minutes with a button that allowed them to give themselves an electric shock on the ankle; many did indeed elect to give themself the brief buzz of pain, seemingly because it was the only way to break up the tedium. Perhaps the same search for an escape explains why bored people turn to unhealthy behaviours – but the upside is that it can also increase innovation.
Returning to those people mindlessly copying out telephone numbers, Mann has found that their ennui boosted their performance standard tests of creativity – such as finding innovative uses for everyday objects. She suspects the tedium encouraged their minds to wander, whichleads to more associative and creative ways of thinking. “If we don’t find stimulation externally, we look internally – going to different places in our minds,” she says. “It allows us to make leaps of imagination. We can get out of the box and think in different ways.” Without the capacity for boredom, then, we humans may have never achieved our artistic and technological heights.
Embracing tedium
Given this benefit, Mann thinks we should try not to fear boredom when it hits us. “We should embrace it,” she says – a philosophy that she has now taken into her own life. “Instead of saying I’m bored when I’m stuck in traffic, I’ll put music on and allow my mind to wander – knowing that it’s good for me. And I let my kids be bored too – because it’s good for their creativity.”
Eastwood is less enthusiastic about boredom’s benefits, but admits we should be cautious about looking for an immediate escape. “The feeling is so aversive that people rush to eliminate it,” he says. “I’m not going to join that war on boredom and come up with a cure, because we need to listen to the emotion and ask what it is trying to tell us to do.”
(Thinkstock)
Fiddling with your smartphone may relieve your immediate tedium but it can't solve longer-term ennui (Thinkstock)
For instance, simply looking for instant gratification on a smartphone or tablet may be counter-productive, he thinks. “We live in tech-driven society where we are overly stimulated – we are constantly yanked around by interruptions,” says Eastwood. That puts us on a kind of treadmill, he says – we keep on expecting quicker and easier ways to revive our curiosity. “One possibility is that this actually makes people more bored.”
Instead, he suggests that it would be wiser to question whether there are more serious, long-term issues that are causing us to feel disengaged. His work, for instance, has shown that priming people to feel their lives have a greater purpose and meaning tends to make them less bored during subsequent tests. Although our feelings of tedium during a work meeting or family gathering might seem superficial annoyances, they could therefore be a symptom of a deeper existential crisis and need for fulfilment that extends far beyond immediate circumstances.

“To feel you can have an effect on the world and that things in life make sense, these are inherently important things for human beings – just like sunlight, fresh air and food,” says Eastwood. As we enter the New Year, that could be as good a reason as any to re-evaluate your life, what you are trying to achieve with it, and to rethink what you actually mean when you say you are bored.

Tuesday, 30 December 2014

How lung cancer spread

Scientists have discovered one way that lung cancer spreads: through the breaking of protein ties that keeps cells together.
The images above depict microscopic photos of such protein ties: on the left, they’re normal, and on the right they are severed. The ones on the right are lung cancer cells; because the tie is broken, they’re way more likely to break down and spread throughout the body. The study was published in Cell Reports and conducted by researchers at the Cancer Research UK Manchester Institute.
The binding keeping cells together is controlled by a protein called TIAM1. When cell maintenance breaks down, TIAM1 gets impaired and allows cells to fall apart, then spread throughout the body.
“This important research shows for the first time how lung cancer cells sever ties with their neighbors and start to spread around the body, by hijacking the cells’ recycling process and sending it into overdrive,” Dr. Angeliki Malliri, a lead author of the study, said in apress release. “Targeting this flaw could help stop lung cancer from spreading.”
Typically, lung cancer spreads to lymph nodes in the chest, abdomen, neck, or armpit, as well as the liver, bones, or brain, according to Cancer Research UK. Lung cancer is particularly likely to spread through the lymph system because it enters lymph vessels around the bronchi in the lungs and begin forming clusters in lymph nodes, which are groups of immune cells.
According to the National Cancer Institute, 2014 saw over 220,000 new cases of lung cancer in the U.S., and about half this number died from lung cancer. In the UK, there are some 43,500 new cases of lung cancer every year, and it's the most common cause of cancer deaths in the UK. “Lung cancer causes more than one in five of all cancer deaths in the UK and it’s vital that we find effective new treatments to fight the disease and save more lives,” Nell Barrie, Cancer Research UK’s senior science information manager, said in the press release.
The authors of the study hope that their research will be one step forward for those looking to stop lung cancer in its tracks once it’s been detected.
“Early stage research like this is essential to find treatments which could one day block cancer spread — which would be a game changer,” Barrie said in the press release. “It’s also crucial that we find ways to diagnose the disease earlier, when treatment is more likely to be successful and the cancer is less likely to have spread.”

Source: Vaughan L, Tan C, Chapman A, Nonaka D, Mack N, Smith D. “HUWE1 Ubiquitylates and Degrades the RAC Activator TIAM1 Promoting Cell-Cell Adhesion Disassembly, Migration, and Invasion.” Cell Reports, 2014.

4 supplements that are better than nootropics

What a fun-looking word:nootropics. It refers to any type of compound or food that has the ability to improve your mental abilities, including your memory, ability to focus, motivation, or even mood. While the general category most definitely includes smart drugs, neuro-enhancing supplements fit the bill as well. Daily, neuroscientists are acquiring a more nuanced understanding of the brain, the result being many new pharmaceutical drugs which target exact regions of the brain are in the works. The very same knowledge, though, might reveal how particular supplements might do an equally good job of improving brain function over the long haul.
Why go for prescription-strength when you can get the same by shopping the vitamin aisle?  
In that spirit, here’s a list of dietary supplements you could investigate for their potential use as a nootropic. Remember: Do your research and ask a doctor’s advice before popping any pill, natural or not. More importantly, not all dietary supplements are created equal, with some brands including additives you may not want (or are allergic to), so it’s important to vet any unfamiliar manufacturers.
Creatine is an old favorite among gym rats, who use it to enhance their sports performance, but over the past decade or so, the supplement’s neuro-enhancing abilities have been demonstrated as well. In one placebo-controlledstudy, researchers tested the hypothesis that 5 grams a day for a six-week period would enhance intelligence test scores while also improving memory. They enlisted the help of 45 young adult, vegetarian subjects and found the supplement had a significant positive effect on both working memory and intelligence, particularly with regard to tasks that require speed of processing. Though they tested vegetarians, the researchers would “expect to see a beneficial effect of creatine supplementation on brain performance in most omnivores apart from those who consume very high amounts of meat.”
Theanine (or more commonly L-theanine) is found in green tea and mushrooms and also sold as a dietary supplement in the United States. In fact, the Food and Drug Administration has granted it GRAS status (generally recognized as safe). According to various scientific studies, theanine has been found to affect the levels of some neurotransmitters, to prevent beta-amyloid-induced brain dysfunction, and to protect against stroke. L-theanine is even said to improve sleep quality in boys with attention deficit hyperactivity disorder. In terms of potential nootropic uses, several small studies indicate a combination of L-theanine and caffeine can improve cognitive performance, particular in the areas of focus and alertness. Apparently, though, the effects may not belong-lasting.
Passionflower is derived from the above ground parts of the plant. Primarily, people take it for itsanti-anxiety effects, which have been proven in smaller scientific studies though not yet confirmed in large scale studies. Some other people use it to treat insomnia as well as neuralgia and withdrawal symptoms while coming off opiates or benzodiazepines. In patients undergoing surgery as well as those about to be treated by a dentist, passionflower has been effectively used to reduce apprehension.
DHA, an omega-3 fatty acid found in fish and seaweed, can improve your memory while protecting against certain psychiatric disorders. Various surveys of people with major depression indicate they have depleted levels of omega-3 fatty acids and one large study found depressive symptoms were significantly higher among infrequent fish consumers. However, no study has ever proven omega-3 fatty acid supplementation effective in relieving major, moderate, or even mild depression. That said, some data suggest it is a safe preventive measure and may reduce the risk of progression of certain psychiatric disorders. While one review of scientific studies found that DHA supplements significantly improves cognitive development in infants — though does not improve cognitive performance in children, adults, or the elderly — another review shows it can protect against mild cognitive impairment, dementia, and the risk and progression of Alzheimer's disease in the elderly.

Sunday, 28 December 2014

Benefits of ginger

Ginger has medicinal value that dates back thousands of years. It's actually the rhizome of the ginger plant, and as a widely cultivated herb, it’s used in various forms across the world in foods, drinks, and beauty products. Ancient texts and literature from the Middle East, Asia, and Europe talk of the immense benefits of the root. It’s also cousins with the famed turmeric root, cardamom, and galangal. In holistic medical practices such as Chinese and Indian Ayurveda, ginger is viewed as a gift from God. And in theQur’an, the Muslim holy book, ginger is also mentioned as a spice found in Heaven.
Ginger's versatility is incredible, and it can be used in your everyday life. Here are some examples of its health benefits:

1.       Blood Flow

Ginger contains chromium, magnesium, and zinc — key ingredients in maintaining healthy and normal blood flow.

2.       Morning Sickness

The American Pregnancy Association recommends consuming ginger in different forms, such as tea or in jam, in order to curb morning nausea brought on by pregnancy. However, in a 2011 study, the information regarding ginger and morning sickness was shown to be more anecdotal. Ginger was helpful in some instances, but the “effectiveness was limited and not consistent” overall. Researchers did suggest that women who wanted to incorporate ginger into their diet should consult their physicians, since it does help some women. 

3.       Improve Metabolism/ Aids Weight Loss

Ginger increases body temperature and can speed up calorie burning sans exercise. It also enhances the thermic effect on foods and makes the body believe that it is full. According to a 2012 study, “ginger showed enhanced thermogenesis and reduced feelings of hunger with ginger consumption.”

4.       Decrease Exercise-Induced Muscle Pain

As a powerful anti-inflammatory, ginger helps to reduce and ease muscle pain. Research in theJournal of Pain found that ginger was superior in its benefits to NSAIDs because it helps to blocks the formation of the inflammatory compounds, prostaglandins and leukotrienes, Discovery Healthreported. The researchers also found that ginger has antioxidant effects, which help to break down pre-existing inflammation.

5.       Inhibit the Growth of Colorectal Cancer Cells

Research at the University of Minnesota's Hormel Institute found that the ingredient that gives ginger its flavor may help to combat the growth of colorectal cancer cells. 

6.       Treat Asthma

Columbia University researcherssay that ginger, paired with bronchodilating medications maybe help to relax the smooth muscle surrounding airways. 

Thursday, 18 December 2014

Habits That Cause Cancer

By now, you may have heard that cancer rates are rising to a point where 44% of men and 39% of women will be diagnosed with the disease. With all the research and drugs being created over the past 30 years, you would think that it would at least be holding steady or declining, but, sadly, that is not the case. So what common patterns are we encountering for these rates to be rising so precipitously throughout North America?

Everyday factors contributing to the rise of cancer


There is a commonly held notion that 'everything' causes cancer nowadays, and although it may often be a flippant response from someone who is frustrated by all the things they need to avoid, it is becoming glaringly obvious that a wide variety of our core activities are indeed contributing to cancer growth.


Behold, a shortened list of these cancer causing factors:


- X-rays
- Sunlight ultraviolet rays
- EMF exposure
- Ionizing, microwave oven, and nonionizing radiation from domestic appliances
- Overhead power lines
- Nuclear radiation
- Pesticides and herbicides
- Industrial toxins
- Drinking or bathing in polluted, chlorinated, or fluoridated water
- Smoking
- Hormonal therapies
- Immune suppressive drugs
- Consuming irradiated foods and food additives
- Mercury toxicity
- Dental fillings, root canals, cavitations and metals
- Use of street, prescription and non-prescription drugs
- Nutritional deficiencies
- Consumption of synthetic 'foods'
- Chronic stress
- Negative emotions
- Depressed thyroid
- Intestinal toxicity
- Parasites
- Viral, bacterial, and fungal infections
- Blocked detoxification pathways
- Genetic predisposition
- Physical irritants (e.g. asbestos)
- Alcohol consumption


One can see from reading the list that many of us are currently, or have extensively in the past, engaged or had many of these challenges.

The only way to halt these scary cancer statistics is to be aware of the factors contributing to cancer, avoid them at all costs and engage in a clean and nourishing lifestyle that does not promote its growth.
 
        What can we do to put the odds more in our favour?

First of all, eat a clean, alkaline diet full of vitamins, minerals, enzymes and probiotics on a daily basis that supports the development of a healthy immune system. Examples of such foods include:
 
- Algae (e.g. chlorella, spirulina)
- Fermented foods (vegetables, kefirs)
- Medicinal mushrooms like reishi and chaga
- Adaptogenic herbs like astragulus, gynostemma, siberian ginseng, goji
- Aloe vera
- Hemp
- Garlic
- Kale
- Broccoli
- Cauliflower
- Watercress
- Cilantro
- Berries
- Pomegranates


Also look to consume pure water, get fresh air, expose yourself to the sunshine for 15-20 minutes a day (don't expose your skin to the point of burning), exercise and consider colonics and coffee enemas.

In contrast, you need to limit or avoid dairy, sugar, grains and animal protein, which are all hard on digestion and the immune system.

This is certainly not an exhaustive list, as entire books are catered to cancer therapies and how to avoid cancer altogether. The core theme in all of them is to:

- Avoid all impurities in food, air and water
- Cleanse your body with alkaline, easily digestible and nutrient rich foods (including necessary whole food supplementation)
- Begin a protocol of liver cleansing and regenerating herbs

Even though it won't be easy, the trends can be reversed. We just need to recognize the power of the body to heal itself when it is given the right medicine and carry out those actions on a consistent basis.

Sunday, 14 December 2014

5 Ways Your Testicles Are Getting Smaller And How To Prevent It

Testicles: they don’t call them a man’s jewels for no reason. After all, they’re the source of all our manliness, producing testosterone daily, which gives us muscle definition, the hair on our faces, and the ability to perform sexually. This should explain, then, why we prize them so much, and why it hits so close to home when people like Tom Green and Lance Armstrong are diagnosed with testicular cancer — both of them got a testicle removed, and Green even had his operation televised.
There’s another condition that’s particularly scary for men: testicular atrophy, colloquially known as shrinking balls. Finding out your balls are shrinking is especially scary because you probably won’t feel anything resembling a tumor underneath, however, you’ll sure as hell be wondering what’s causing it and if you’re in danger of anything. If you ever find yourself going from walnuts to grapes down there, it could be because of one of these five reasons.

No Sleep for Shrinking Balls

In case you haven’t heard, sleep is extremely important to our overall health. Not only does it restore physical energy but it also restores our capacity for attention and memory, and boosts metabolism and heart health. Even better, it puts us in good moods.
Some research, however, suggests that losing sleep can shrink the balls. In a study from last year, researchers at the University of Southern Denmark surveyed nearly 1,000 young men about their sleep schedules, interruptions in sleep, and other habits. They also took blood samples and measured sperm counts, and found that men who had problems sleeping — insomnia, going to sleep late, or inconsistent sleep — had a 29 percent drop in sperm count. What’s more, their sperm were 1.6 percent more likely to be deformed, and their testicles had shrunk.
The researchers also noted that people who sleep late are more likely to lead unhealthier lifestyles, which could include smoking and drinking, but even then, it’s a good reason to get more sleep.

What’s That About Alcohol?

We all love our drinks in one way or another, whether they’re glammed up with fruity flavors or served neat. Alcohol has been found to benefit our health in many ways; red wine’s resveratrol is a relatively powerful antioxidant, and a drink or two can boost our creativity. But just like most things, drink too much, and you’re more likely to harm your body than help it.
Such is the case with alcohol and testicular size. In a study published this September, researchers found through both in vivo and in vitro studies on rats that alcohol caused changes to Leydig cell shape and function. These cells are located adjacent to the testicles’ seminiferous tubules, which are where sperm cells are produced. In turn, the tubules shrunk, and subsequent processes involving the way alcohol alters testicular energy metabolism and sperm cell mitochondria led to cell death. Together, these processes led to testicular shrinkage in the rats, and the researchers believe the same may be true for humans.
The good news, however, and it’s rather huge: All you have to do is quit drinking, and your testicles will likely bounce back to the size they were before.

Aluminum, Who Knew?

Okay so, most of us love to eat. And what keeps our food warm when we don’t have an actual heat source? That’s right, aluminum foil. Depending on the types of food you’re eating, the metal could be leaching in, and you’re eating it. But aluminum is found in other things too, such as tobacco, alcohol (here we go again), and even in the air.
Exposure to too much aluminum may cause a low sperm count and infertility, and a side effect of smaller testicles. In a study from last month, researchers examined 62 sperm samples and measured aluminum content, finding average of 339 parts per billion (high), with some men even having aluminum has high as 500 parts per billion. Those with the higher levels of aluminum were more likely to have low sperm counts and were therefore less fertile. Such exposure may lead to oxidative stress in the testicles, causing cells to die, and the testicles to shrink.
Limiting aluminum exposure by choosing chemical-free cleaning and personal care products may help, as well as using BPA-free plastic or glass bottles for drinking, rather than plain plastic.

Getting Kicked One Too Many Times, As If You Didn’t Suspect It Already

Our testicles have perhaps the most pain receptors concentrated in any one area of our bodies. We need them because they are the key to our reproductive success, even as they hang outside our bodies, vulnerable to attack. Getting kicked in the balls is enough to knock even the strongest man to his knees, as the pain receptors send signals through nerves that extend to the ears, stomach, and groin.
Thankfully, many men’s testicles don’t experience such trauma daily — except for those into skateboarding. For these certain groups, or those who experience one serious hit, the balls may indeed shrink. A study from 1999 (kind of outdated, yeah, but still relevant) found that 50 percent of men who experienced “blunt scrotal trauma” saw a reduction in the volume of the injured testicle.
Thankfully, getting hit in this area is relatively rare. But if you want to be extra safe, you can get yourself a cup.

Smoke Your Balls Away... with Marijuana?

Data has been conflicting for years on many of the long-term effects of marijuana. Studies have suggested that long-term use affects the brain’s reward system, causes brain damage, and lowers kids’ school grades. But for each study that finds a problem with it, there’s another one that puts the concern back at square one.
Testicular atrophy is one such issue, although many of the studies suggesting it does cause shrinkage are relatively outdated — from the 1980s. Nevertheless, the majority of it suggests that smoking weed lowers testosterone levels, either directly or through precursor hormones; or causes testicular atrophy in monkeys and dogs. A study from 2012 revives this idea, and finds some evidence in men living in the Niger delta area of Nigeria. In that study, 75 men who smoked marijuana were also likely to have shrunken testicles, infertility, and even male breasts.
The takeaway from all of this is that it’s really just too inconclusive. Each one of the 1980s studies found that while it may have altered certain factors that could lead to atrophy, the effects weren’t long lasting. Within 24 hours to three days, testicles began to grow back to normal size. So, if you’re really worried about whether your marijuana use is causing your balls to shrink, it’s probably best to stop. But it seems that continuing might only have temporary effects, if any at all.
All of this is surely informative, and may help at hinting what’s causing your testicles to shrink. But if you suspect you have testicular atrophy, the best thing you can do is to consult a doctor. We mean it.

Drinking Alcohol Makes You More Creative

Advertising has and forever will be one of the most creative industries out there. In the 1960s, Volkswagen’s “Lemon” advertisement for the beetle, which showed the word big and bold, ushered in the so-called “creative revolution” throughout advertising agencies. Rather than cliché ads, which only showed the product and the reason for its use — a hammer hitting a head for headache medicine — the word “Lemon” captured people’s attention, and then told them something about the product that was completely unrelated to lemons. If you watch Mad Men, then you know how much drinking is portrayed during that time period. But it was very much the same in reality, and that’s because alcohol certainly does make you more creative.
“When you work hard all day with your head and know you must work again the next day, what else can change your ideas and make them run in a different plane like whisky?” Ernest Hemmingway once said, and he wasn’t alone. Famed authors David Foster Wallace, Edgar Allan Poe, and Truman Capote were also heavy drinkers, along with countless musicians and celebrities. Although heavy drinking won’t necessarily get you thinking more creatively, a couple could help you hone your craft if you’re trying to be creative. It probably won’t help for other things though.

What is Creativity?

Although many believe the left hemisphere is responsible for practical, logical and organized thought, and the right is where creativity comes from, it’s much more complex. First, it depends on what someone is trying to create. Once that happens, three different networks in the brain work together: the Executive Attention Network (EAN), the Imagination Network (IN), and the Salience Network (SN).
The EAN activates when a problem requires complete concentration. It depends largely on working memory and complex problem solving, as neural connections between the outer regions of the prefrontal cortex and the back of the parietal lobe are tasked with being efficient and reliable. The IN creates mental simulations about almost anything from possible future experiences to imagining other people’s perspectives, and involves neural connections between the deeper regions of the prefrontal cortex and the temporal lobe. Meanwhile, the SI monitors events occurring outside of the body as well as internal consciousness, and is able to direct attention to whatever is more important at a certain moment in time.
Together these three can either work together for the greater good of being creative, or they may clash, causing creativity to diminish. The researchers who developed this framework, from the Department of Neurosurgery at the University of New Mexico, believe that reducing activation in the EAN by just a little bit can boost the ability of a person’s mind to wander, loosen up, and imagine more creatively, as the energy that went to the EAN gets shifted to the IN and SN. And that’s where booze can help.

Drink Up and Broaden Your Imaginary Horizons

Alcohol worsens our working memory and impedes the brain’s executive processes, causing us also to become unaware of what’s going on around us and unable to concentrate on tasks at hand. That’s why people can’t drink and drive, or operate heavy machinery — they’re just not going to do it right. But what’s lost in our ability to focus is gained in our ability to think creatively. In 2012, researchers from the University of Illinois showed how creative people could be when happily drunk.
Their study, “Uncorking the Muse: Alcohol Intoxication Facilitates Creative Problem Solving,” looked at the ability of 40 men, whose blood alcohol content was 0.075 (just under the legal limit), to solve a creative problem-solving task. Called the Remote Associates Test (RAT), participants were given three words, such as “peach,” “arm,” and “tar,” and asked to come up with another word that could go with each to form a two-word phrase — in this case, the word was “pit.” The test works because the most obvious responses are usually incorrect, forcing participants to think creatively. Indeed, all of the intoxicated participants came up with correct answers, and they were more “insightful,” too.
Another study, called the “Newt/Judge Experiment,” involved 18 advertising creatives who were split into two groups. One group was allowed to drink all the alcohol they wanted, while the other group could only get water. For three hours, each group worked on an ad campaign about binge drinking, and at the end of the brainstorming, a group of top creative directors judged each idea.
As you’d probably expect, the drinkers came out on top, with four out of the five best ideas, as well as the most ideas. These included seats that were only for people drinking water and water bottles as club tickets — the label had the club name and someone would only be allowed in if the bottle was empty. Then, to get a second opinion, the experimenters asked groups of pub goers, ages 18 to 30, which ones they liked. Again, the drinkers’ ideas were chosen as better.

Drink, Relax the Brain, and Aha!

Researcher Mark Beeman, from Northwestern University, conducted two experiments with researchers from Drexel University, which looked at the source of the “Eureka,” or “Aha!” moment. Using brain scans, they found that participants who were concentrating too hard would sometimes block the creative processes necessary for problem solving (i.e. writers' block). But among participants who were relaxed, and not thinking about solving their problems, moments of “Eureka” were preceded by an upsurge of activity — only 1.5 seconds before — in the superior temporal gyrus, an area of the brain directly above the ear.
So, considering that drinking makes you relaxed, there’s a higher chance you’ll have an “Aha!” moment. Pair that with alcohol’s ability to reduce function in executive function, while boosting imagination and inner consciousness, and it looks like drinking will make you more creative. Drink too much, though, and you might end up passing out.

Scientists Discover Children’s Cells Living in Mothers’ Brains

The link between a mother and child is profound, and new research suggests a physical connection even deeper than anyone thought. The profound psychological and physical bonds shared by the mother and her child begin during gestation when the mother is everything for the developing fetus, supplying warmth and sustenance, while her heartbeat provides a soothing constant rhythm.
The physical connection between mother and fetus is provided by the placenta, an organ, built of cells from both the mother and fetus, which serves as a conduit for the exchange of nutrients, gasses, and wastes. Cells may migrate through the placenta between the mother and the fetus, taking up residence in many organs of the body including the lung, thyroid muscle, liver, heart, kidney and skin. These may have a broad range of impacts, from tissue repair and cancer prevention to sparking immune disorders.
It is remarkable that it is so common for cells from one individual to integrate into the tissues of another distinct person. We are accustomed to thinking of ourselves as singular autonomous individuals, and these foreign cells seem to belie that notion, and suggest that most people carry remnants of other individuals. As remarkable as this may be, stunning results from a new study show that cells from other individuals are also found in the brain. In this study, male cells were found in the brains of women and had been living there, in some cases, for several decades. What impact they may have had is now only a guess, but this study revealed that these cells were less common in the brains of women who had Alzheimer’s disease, suggesting they may be related to the health of the brain.
We all consider our bodies to be our own unique being, so the notion that we may harbor cells from other people in our bodies seems strange. Even stranger is the thought that, although we certainly consider our actions and decisions as originating in the activity of our own individual brains, cells from other individuals are living and functioning in that complex structure. However, the mixing of cells from genetically distinct individuals is not at all uncommon. This condition is called chimerism after the fire-breathing Chimera from Greek mythology, a creature that was part serpent part lion and part goat. Naturally occurring chimeras are far less ominous though, and include such creatures as the slime mold and corals.
 Microchimerism is the persistent presence of a few genetically distinct cells in an organism. This was first noticed in humans many years ago when cells containing the male “Y” chromosome were found circulating in the blood of women after pregnancy. Since these cells are genetically male, they could not have been the women’s own, but most likely came from their babies during gestation.
In this new study, scientists observed that microchimeric cells are not only found circulating in the blood, they are also embedded in the brain. They examined the brains of deceased women for the presence of cells containing the male “Y” chromosome. They found such cells in more than 60 percent of the brains and in multiple brain regions. Since Alzheimer’s disease is more common in women who have had multiple pregnancies, they suspected that the number of fetal cells would be greater in women with AD compared to those who had no evidence for neurological disease. The results were precisely the opposite: there were fewer fetal-derived cells in women with Alzheimer’s. The reasons are unclear.
Microchimerism most commonly results from the exchange of cells across the placenta during pregnancy, however there is also evidence that cells may be transferred from mother to infant through nursing. In addition to exchange between mother and fetus, there may be exchange of cells between twins in utero, and there is also the possibility that cells from an older sibling residing in the mother may find their way back across the placenta to a younger sibling during the latter’s gestation. Women may have microchimeric cells both from their mother as well as from their own pregnancies, and there is even evidence for competition between cells from grandmother and infant within the mother.
What it is that fetal microchimeric cells do in the mother’s body is unclear, although there are some intriguing possibilities. For example, fetal microchimeric cells are similar to stem cells in that they are able to become a variety of different tissues and may aid in tissue repair. One research group investigating this possibility followed the activity of fetal microchimeric cells in a mother rat after the maternal heart was injured: they discovered that the fetal cells migrated to the maternal heart and differentiated into heart cells helping to repair the damage. In animal studies, microchimeric cells were found in maternal brains where they became nerve cells, suggesting they might be functionally integrated in the brain. It is possible that the same may true of such cells in the human brain.
These microchimeric cells may also influence the immune system. A fetal microchimeric cell from a pregnancy is recognized by the mother’s immune system partly as belonging to the mother, since the fetus is genetically half identical to the mother, but partly foreign, due to the father’s genetic contribution. This may “prime” the immune system to be alert for cells that are similar to the self, but with some genetic differences. Cancer cells which arise due to genetic mutations are just such cells, and there are studies which suggest that microchimeric cells may stimulate the immune system to stem the growth of tumors. Many more microchimeric cells are found in the blood of healthy women compared to those with breast cancer, for example, suggesting that microchimeric cells can somehow prevent tumor formation. In other circumstances, the immune system turns against the self, causing significant damage. Microchimerism is more common in patients suffering from Multiple Sclerosis than in their healthy siblings, suggesting chimeric cells may have a detrimental role in this disease, perhaps by setting off an autoimmune attack.
This is a burgeoning new field of inquiry with tremendous potential for novel findings as well as for practical applications. But it is also a reminder of our interconnectedness.